Article
GABI-DUPLO: a collection of double mutants to overcome genetic redundancy in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology - 1 Jul 2013
Bolle Cordelia, Huep Gunnar, Kleinbölting Nils, Haberer Georg, Mayer Klaus, Leister Dario, Weisshaar Bernd
Abstract excerpt
Owing to duplication events in its progenitor, more than 90% of the genes in the Arabidopsis thaliana genome are members of multigene families. A set of 2108 gene families, each consisting of precisely two unlinked paralogous genes, was identified in the nuclear genome of A. thaliana on the basis of sequence similarity. A systematic method for the creation of double knock-out lines for such gene pairs, designated...
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