Article
Regulation of transcription of the murine gamma-glutamyl hydrolase gene. Delineation of core promoter A and the role of LYF-1, E2F and ETS-1 in determining tumor-specific expression.
Gene - 29 May 2002
Masumoto Naoko, Chen Jing, Sirotnak F M
Abstract excerpt
Our earlier studies (Gene 268 (2001) 183) showed that transcription of the mouse gamma-glutamyl hydrolase (gamma GH) gene is under the control of two separate promoters widely distributed within the genome. We now report on further studies examining the functional characteristics of the more efficient promoter (promoter A) which is contiguous with an exon 1 (exon A1a) alternate within the main body of the gene....
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