Article
Cloning of mouse gamma-glutamyl hydrolase in the form of two cDNA variants with different 5' ends and encoding alternate leader peptide sequences.
Gene - 28 Sept 1998
Esaki T, Roy K, Yao R, Galivan J, Sirotnak F M
Abstract excerpt
Mouse-liver gamma-glutamyl hydrolase (GH) is a lysosomal endopeptidase with an acid pH optimum that is activated by sulfhydryl compounds and preferentially hydrolyzes the most proximal gamma-glutamyl linkage of longer chain polyglutamates of folates and their analogues. We describe the cloning of this mouse lysosomal cDNA enzyme from liver GH mRNA in the form of two cDNA variants (1.295 and 1.268 kb in length)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
