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Article

hMLH1 immunoexpression is related to the degree of epithelial dysplasia in oral leukoplakia

24 Oct 2010

Abstract excerpt

BACKGROUND: hMLH1 is a protein of the mammalian mismatch repair system responsible for genomic stability during repeated duplication. Relation between its altered expression linked to microsatellite instability has also been observed in oral leukoplakias (OL) and squamous cell carcinomas pointing to a possible role of hMLH1 in oral carcinogenesis. To our knowledge, this is the first study evaluating the...

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PMID: 20969633
DOI: 10.1111/j.1600-0714.2010.00963.x

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