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Article

Immunohistochemical analysis of expression and allelotype of mismatch repair genes (hMLH1 and hMSH2) in bladder cancer.

British journal of cancer - 2 Feb 2001

Kassem H S, Varley J M, Hamam S M, Margison G P

Abstract excerpt

Mutation of human homologues of DNA mismatch repair (MMR) genes in tumours has been shown to be associated with the phenomenon of microsatellite instability (MSI). Several studies have reported the occurrence of MSI in bladder cancer, but evidence of involvement of MMR genes in the pathogenesis of this cancer is still unclear. We therefore utilized quantitative immunohistochemical (IHC) image analysis and...

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Share to Adaptor Proteins, Signal Transducing
Share to Allelic Imbalance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Loss of Heterozygosity

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Source

Open in PubMed Open full text

Identifiers

PMID: 11161395
DOI: 10.1054/bjoc.2000.1595
PMCID: PMC2363732

Genes

MSH2
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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