Article
Noncatalytic domains of RGS9-1.Gbeta 5L play a decisive role in establishing its substrate specificity.
The Journal of biological chemistry - 6 Sept 2002
Martemyanov Kirill A, Arshavsky Vadim Y
Abstract excerpt
The complex between the photoreceptor-specific regulator of G protein signaling (RGS) protein, RGS9-1, and type 5 G protein beta-subunit, Gbeta5L, regulates the duration of the cellular response to light by stimulating the GTPase activity of G protein, transducin. An important property of RGS9-1.Gbeta5L is that it interacts specifically with transducin bound to its effector, cGMP phosphodiesterase, rather than...
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