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Article

Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor.

Molecular endocrinology (Baltimore, Md.) - 1 Jul 2002

Cheng Shinta, Brzostek Sabrina, Lee Suzanne R, Hollenberg Anthony N, Balk Steven P

Abstract excerpt

Nuclear receptor corepressor (NCoR) mediates transcriptional repression by unliganded nuclear receptors and certain steroid hormone receptors (SHRs) bound to nonphysiological antagonists, but has not been found to regulate SHRs bound to their natural ligands. This report demonstrates that NCoR interacts directly with the androgen receptor (AR) and represses dihydrotestosterone-stimulated AR transcriptional...

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Share to Dihydrotestosterone
Share to Histone Deacetylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammals

Share to Nuclear Proteins

Share to Receptors, Androgen

Share to Repressor Proteins

Share to Transcription, Genetic

Share to Two-Hybrid System Techniques

Source

Identifiers

PMID: 12089345
DOI: 10.1210/mend.16.7.0870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor.PMID 12089345Read ↗

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