Article
Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).
The Biochemical journal - 1 May 2004
Berrevoets Cor A, Umar Arzu, Trapman Jan, Brinkmann Albert O
Abstract excerpt
Antiandrogens are widely used agents in the treatment of prostate cancer, as inhibitors of AR (androgen receptor) action. Although the precise mechanism of antiandrogen action is not yet elucidated, recent studies indicate the involvement of nuclear receptor co-repressors. In the present study, t...
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