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Article

Mouse models of neurofibromatosis 1 and 2.

Neoplasia (New York, N.Y.) - 1 Jan 2000

Gutmann David H, Giovannini Marco

Abstract excerpt

The neurofibromatoses represent two of the most common inherited tumor predisposition syndromes affecting the nervous system. Individuals with neurofibromatosis 1 (NF1) are prone to the development of astrocytomas and peripheral nerve sheath tumors whereas those affected with neurofibromatosis 2 (NF2) develop schwannomas and meningiomas. The development of traditional homozygous knockout mice has provided...

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Identifiers

PMID: 12082543
DOI: 10.1038/sj.neo.7900249
PMCID: PMC1531708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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