Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments.

The Journal of cell biology - 24 Jun 2002

Al-Bassam Jawdat, Ozer Rachel S, Safer Daniel, Halpain Shelley, Milligan Ronald A

Abstract excerpt

MAP2 and tau exhibit microtubule-stabilizing activities that are implicated in the development and maintenance of neuronal axons and dendrites. The proteins share a homologous COOH-terminal domain, composed of three or four microtubule binding repeats separated by inter-repeats (IRs). To investigate how MAP2 and tau stabilize microtubules, we calculated 3D maps of microtubules fully decorated with MAP2c or tau...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Cytoskeleton
Share to Imaging, Three-Dimensional

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microtubule-Associated Proteins

Share to Microtubules

Share to Recombinant Fusion Proteins

Share to tau Proteins

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 12082079
DOI: 10.1083/jcb.200201048
PMCID: PMC2173547

Genes

MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments.PMID 12082079Read ↗

The MAP1 family of microtubule-associated proteins.Semantic proximity Read ↗

Atomic model of microtubule-bound tauSemantic proximity Read ↗

Molecular characterization of microtubule-associated proteins tau and map2Semantic proximity Read ↗

Regulated association of microtubule-associated protein 2 (MAP2) with Src and Grb2: evidence for MAP2 as a scaffolding protein.Semantic proximity Read ↗

A TIRF microscopy assay to decode how tau regulates EB's tracking at microtubule ends.Semantic proximity Read ↗

Lysate-based pipeline to characterize microtubule-associated proteins uncovers unique microtubule behaviours.Semantic proximity Read ↗

Structural basis for CRMP2-induced axonal microtubule formation.Semantic proximity Read ↗

Functional analysis of the MAP2 repeat domain.Semantic proximity Read ↗

CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.Semantic proximity Read ↗

Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules.Semantic proximity Read ↗

A new look at the microtubule binding patterns of dimeric kinesins.Semantic proximity Read ↗

Tau avoids the GTP cap at growing microtubule plus endsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.