Article
A TIRF microscopy assay to decode how tau regulates EB's tracking at microtubule ends.
Methods in cell biology - 1 Jan 2017
Ramirez-Rios Sacnicte, Serre Laurence, Stoppin-Mellet Virginie, Prezel Elea, Vinit Angélique, Courriol Emilie, Fourest-Lieuvin Anne, Delaroche Julie, Denarier Eric, Arnal Isabelle
Abstract excerpt
Tau is a major microtubule-associated protein (MAP) mainly expressed in the brain. Tau binds the lattice of microtubules and favors their elongation and bundling. Recent studies have shown that tau is also a partner of end-binding proteins (EBs) in neurons. EBs belong to the protein family of the plus-end tracking proteins that preferentially associate with the growing plus-ends of microtubules and control...
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