Article
Attention-deficit/hyperactivity disorder (ADHD): feasibility of linkage analysis in a genetic isolate using extended and multigenerational pedigrees.
Clinical genetics - 1 May 2002
Arcos-Burgos M, Castellanos F X, Lopera F, Pineda D, Palacio J D, Garcia M, Henao G C, Palacio L G, Berg K, Bailey-Wilson J E, Muenke M
Abstract excerpt
Segregation analyses converge in explaining the predisposition to attention-deficit/hyperactivity disorder (ADHD) as the consequence of a major gene and exclude purely environmental or cultural transmission. As a result of the ADHD phenotype restrictions, collection of extended families or design of linkage studies using families has been extremely difficult and thus currently linkage studies have been performed...
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