Article
Haplotype co-segregation with attention deficit-hyperactivity disorder in unrelated German multi-generation families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2013
Lin Michelle K, Freitag Christine M, Schote Andrea B, Pálmason Haukur, Seitz Christiane, Renner Tobias J, Romanos Marcel, Walitza Susanne, Jacob Christian P, Reif Andreas, Warnke Andreas, Cantor Rita M, Lesch Klaus-Peter, Meyer Jobst
Abstract excerpt
Complex disorders have proved to be elusive in the search for underlying genetic causes. In the presence of large multi-generation pedigrees with multiple affected individuals, heritable familial forms of the disorders can be postulated. Observations of particular chromosomal haplotypes shared among all affected individuals within pedigrees may reveal chromosomal regions, in which the disease-related genes may be...
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