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Article

Pedigree disequilibrium test (PDT) replicates association and linkage between DRD4 and ADHD in multigenerational and extended pedigrees from a genetic isolate.

Molecular psychiatry - 1 Mar 2004

Arcos-Burgos M, Castellanos F X, Konecki D, Lopera F, Pineda D, Palacio J D, Rapoport J L, Berg K, Bailey-Wilson J, Muenke M

Abstract excerpt

Association/linkage between dopamine D4 receptor (DRD4) polymorphisms and attention-deficit/hyperactivity disorder (ADHD) has been suggested by case-control- and nuclear-family-based studies. Here, we present a candidate gene analysis for DRD4 using 14 extended and multigenerational families segregating ADHD derived from the 'Paisa' community of Antioquia, Colombia, a genetic isolate. Two DRD4 polymorphisms (a...

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Source

Identifiers

PMID: 15094785
DOI: 10.1038/sj.mp.4001396

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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