Article
[Linkage analysis in an extended multigenerational family segregating for idiopathic epilepsy].
Revista de neurologia - 1 Jan 2000
Palacio L G, Sánchez J L, Jiménez M E, Rivera-Valencia D, Jiménez-Ramírez I, Arcos O M
Abstract excerpt
INTRODUCTION: Linkage analyses enable us to identify the loci that bestow susceptibility to certain diseases which are assumed to have a genetic aetiology by determining the cosegregation of alleles of specific markers within families. AIMS: The aim of this study was to determine whether there is generalised idiopathic epilepsy (GIE) susceptibility in the 8q22.1 -q24.23, 16p13.3 and 21q22.3 regions within an...
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