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The p53MH algorithm and its application in detecting p53-responsive genes

19 Jun 2002

Abstract excerpt

A computer algorithm, p53MH, was developed, which identifies putative p53 transcription factor DNA-binding sites on a genomewide scale with high power and versatility. With the sequences from the human and mouse genomes, putative p53 DNA-binding elements were identified in a scan of 2,583 human genes and 1,713 mouse orthologs based on the experimental data of el-Deiry et al. [el-Deiry, W. S., Kern, S. E.,...

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PMID: 12077306
DOI: 10.1073/pnas.132268899

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