Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2002

Guethlein Lisbeth A, Flodin Laura R, Adams Erin J, Parham Peter

Abstract excerpt

CD94, NKG2, Ly49, and killer cell Ig-like receptor (KIR) expressed by orangutan peripheral blood cells were examined by cloning and sequencing cDNA from a panel of individuals. Orthologs of human CD94, NKG2A, D, and F were defined. NKG2C and E are represented by one gene, Popy-NKG2CE, that is equidistant from the two human genes. Several Popy-CD94, NKG2A, and NKG2CE alleles were defined. Popy-Ly49L is expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Ly
Share to HLA-C Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins

Share to Lectins, C-Type

Share to NK Cell Lectin-Like Receptor Subfamily C

Share to Pongo pygmaeus

Share to Receptors, KIR

Share to Receptors, Natural Killer Cell

Source

Identifiers

PMID: 12077248
DOI: 10.4049/jimmunol.169.1.220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C.PMID 12077248Read ↗

Conservation and variation in human and common chimpanzee CD94 and NKG2 genes.Semantic proximity Read ↗

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.Semantic proximity Read ↗

High diversification of CD94 by alternative splicing in New World primates.Semantic proximity Read ↗

The KIR repertoire of a West African chimpanzee population is characterized by limited gene, allele, and haplotype variation.Semantic proximity Read ↗

KIR: diverse, rapidly evolving receptors of innate and adaptive immunity.Semantic proximity Read ↗

Major histocompatibility complex class-I-interacting natural killer cell receptors of nonhuman primates.Semantic proximity Read ↗

Genomics and diversity of the common marmoset monkey NK complex.Semantic proximity Read ↗

Killer cell immunoglobulin-like receptor diversity: balancing signals in the natural killer cell response.Semantic proximity Read ↗

The genetic and evolutionary balances in human NK cell receptor diversity.Semantic proximity Read ↗

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts.Semantic proximity Read ↗

Co-evolution of MHC class I and variable NK cell receptors in placental mammals.Semantic proximity Read ↗

Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.