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Article

Conservation and variation in human and common chimpanzee CD94 and NKG2 genes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2002

Shum Benny P, Flodin Laura R, Muir David G, Rajalingam Raja, Khakoo Salim I, Cleland Sophia, Guethlein Lisbeth A, Uhrberg Markus, Parham Peter

Abstract excerpt

To assess polymorphism and variation in human and chimpanzee NK complex genes, we determined the coding-region sequences for CD94 and NKG2A, C, D, E, and F from several human (Homo sapiens) donors and common chimpanzees (Pan troglodytes). CD94 is highly conserved, while the NKG2 genes exhibit some polymorphism. For all the genes, alternative mRNA splicing variants were frequent among the clones obtained by...

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PMID: 11751968
DOI: 10.4049/jimmunol.168.1.240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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