The inducible <i>N</i> -acetylglucosamine catabolic pathway gene cluster in <i>Candida albicans</i> : Discrete <i>N</i> -acetylglucosamine-inducible factors interact at the promoter of <i>NAG1</i>

Abstract excerpt

The catabolic pathway of N-acetylglucosamine (GlcNAc) in Candida albicans is an important facet of its pathogenicity. One of the pathway genes, encoding glucosamine-6-phosphate deaminase (NAG1) is transcriptionally regulated by GlcNAc. Sequence analysis of a 4-kb genomic clone containing NAG1 indicates that this gene is part of a cluster containing two other genes of the GlcNAc catabolic pathway, i.e., DAC1,...

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