Article
Diagnosis of gastrointestinal stromal tumors: a consensus approach.
International journal of surgical pathology - 1 Apr 2002
Fletcher Christopher D M, Berman Jules J, Corless Christopher, Gorstein Fred, Lasota Jerzy, Longley B Jack, Miettinen Markku, O'Leary Timothy J, Remotti Helen, Rubin Brian P, Shmookler Barry, Sobin Leslie H, Weiss Sharon W
Abstract excerpt
As a result of major recent advances in understanding the biology of gastrointestinal stromal tumors (GIST), specifically recognition of the central role of activating KIT mutations and associated KIT protein expression in these lesions, and the development of novel and effective therapy for GISTs using the receptor tyrosine kinase inhibitor STI-571, these tumors have become the focus of considerable attention...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.