Article
The reappraisal of gastrointestinal stromal tumors: from Stout to the KIT revolution.
Virchows Archiv : an international journal of pathology - 1 May 2003
Dei Tos Angelo P
Abstract excerpt
For five decades gastrointestinal stromal tumors (GISTs) truly have represented one of the most confusing as well as neglected areas of both surgical pathology and clinical oncology. The recognition of the central role played by KIT expression in the development of the interstitial cell of Cajal and of the activating KIT mutations in the pathogenesis of GIST have been the keys for a more precise categorization of...
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