Article
Everything you always wanted to know about GIST (but were afraid to ask) An update on GIST pathology.
Pathologica - 1 Sept 2016
Ricci R, Saragoni L
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. The discovery of the occurrence of activating KIT mutations and KIT expression in GISTs opened the way to the unequivocal diagnosis of these tumors and to their successful treatment with imatinib, a tyrosin kinase inhibitor. Since then, research progress revealed molecular GIST triggers alternative to...
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