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Article

Nuclear mitochondrial interplay in the modulation of the homopolymeric tract length heteroplasmy in the control (D-loop) region of the mitochondrial DNA.

Human genetics - 1 May 2002

Malik Safarina, Sudoyo Herawati, Pramoonjago Patcharin, Suryadi Helena, Sukarna Tika, Njunting Marleisje, Sahiratmadja Edhyana, Marzuki Sangkot

Abstract excerpt

We have studied the genetic characteristics of a homopolymeric tract length heteroplasmy associated with the 16189C variant in the mtDNA D-loop control region to identify the factor(s) involved in the generation of the length heteroplasmy. The relative proportion of the various lengths of the polycytosines (i.e., the pattern of the length heteroplasmy) is maintained in an individual, and previous evidence shows...

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PMID: 12073009
DOI: 10.1007/s00439-002-0717-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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