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Article

MtDNA substitution rate and segregation of heteroplasmy in coding and noncoding regions.

Human genetics - 1 Jul 2000

Cavelier L, Jazin E, Jalonen P, Gyllensten U

Abstract excerpt

The mitochondrial DNA (mtDNA) substitution rate and segregation of heteroplasmy were studied for the non-coding control region (D-loop) and 500 bp of the coding region between nucleotide positions 5550 and 6050, by sequence analysis of blood samples from 194 individuals, representing 33 maternal lineages. No homoplasmic nucleotide substitutions were detected in a total of 292 transmissions. The estimated...

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Identifiers

PMID: 10982034
DOI: 10.1007/s004390000305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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