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Article

Evidence for the de novo regeneration of the pattern of the length heteroplasmy associated with the T16189C variant in the control (D-loop) region of mitochondrial DNA.

Journal of human genetics - 1 Jan 2002

Malik Safarina, Sudoyo Herawati, Pramoonjago Patcharin, Sukarna Tika, Darwis Dina, Marzuki Sangkot

Abstract excerpt

We have investigated the genetics of the length heteroplasmy associated with the T16189C variant of mitochondrial DNA (mtDNA), and report here definitive evidence that the pattern of the length heteroplasmy is not simply the outcome of drift related to the random segregation of the mtDNA population during cell division, but is actively maintained and regenerated de novo following each cell division. The pattern...

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PMID: 11950064
DOI: 10.1007/s100380200013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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