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Article

Evaluating length heteroplasmy in the human mitochondrial DNA control region.

International journal of legal medicine - 1 Mar 2010

Forster Lucy, Forster Peter, Gurney Susan M R, Spencer Matthew, Huang Christopher, Röhl Arne, Brinkmann Bernd

Abstract excerpt

We present allelic data for three known and one new C-tract in the human mitochondrial DNA (mtDNA) control region, and we measure intergenerational mutation rates at such C-tracts. In detail, in a sample of 1,172 mtDNA sequences, we demonstrate the existence of an instability threshold of eight consecutive cytosines, at and above which the phenomenon of length heteroplasmy arises. To determine mutation rates, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19937256
DOI: 10.1007/s00414-009-0385-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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