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Article

Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Mar 2022

Baril Andrée-Ann, Beiser Alexa S, Sanchez Erlan, Mysliwiec Vincent, Redline Susan, Gottlieb Daniel J, O'Connor George T, Gonzales Mitzi M, Himali Dibya, Seshadri Sudha, Himali Jayandra J, Pase Matthew P

Abstract excerpt

INTRODUCTION: We evaluated whether insomnia symptom severity was associated with cognitive function, and whether this relationship was modified by biomarkers associated with Alzheimer's disease risk. METHODS: We examined insomnia symptoms and neuropsychological performance 3.4 years later in 511 dementia-free Framingham Heart Study participants (62.65 ± 8.7 years, 50.9% male). Additionally, we explored insomnia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34310026
DOI: 10.1002/alz.12405
PMCID: PMC8802306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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