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Article

Nocturnal sleep apnea/hypopnea is associated with lower memory performance in APOE epsilon4 carriers.

Neurology - 23 Aug 2005

O'Hara R, Schröder C M, Kraemer H C, Kryla N, Cao C, Miller E, Schatzberg A F, Yesavage J A, Murphy G M

Abstract excerpt

The authors investigated the relationship between obstructive sleep apnea/hypopnea (OSAH) and cognition in 36 older adults, 18 APOE epsilon4 carriers, and 18 non-carriers. Greater numbers of respiratory events negatively impacted memory function in epsilon4 carriers only. This is the first study to provide preliminary evidence for a negative interaction of APOE epsilon4 and OSAH on memory in older adults, which...

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Source

Identifiers

PMID: 16116137
DOI: 10.1212/01.wnl.0000173055.75950.bf

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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