Article
Sequencing of the second exon of the MHC class II DQ6 alleles in patients with type 1 diabetes.
Autoimmunity - 1 Mar 2002
Rayner M L, Kelly M A, Mijovic C H, Barnett A H
Abstract excerpt
The MHC class II molecule DQ6 is strongly associated with protection from type 1 diabetes. A small number of diabetic subjects have been typed as positive for DQ6, but it has been suggested that these individuals may possess a mutant form of the molecule, which is structurally altered in such a way as to abrogate its protective effect. In order to test this hypothesis, eight diabetic individuals positive for DQ6...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.