Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmaceutical strategies utilizing recombinant human serum albumin.

Pharmaceutical research - 1 May 2002

Chuang Victor Tuan Giam, Kragh-Hansen Ulrich, Otagiri Masaki

Abstract excerpt

Gene manipulation techniques open up the possibility of making recombinant human serum albumin (rHSA) or mutants with desirable therapeutic properties and for protein fusion products. rHSA can serve as a carrier in synthetic heme protein, thus reversibly carrying oxygen. Myristoylation of insulin results in a prolonged half-life because of self aggregation and increased albumin binding. Preferential albumin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Blood-Brain Barrier
Share to Drug Carriers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Vectors

Share to Insulin

Share to Microspheres

Share to Recombinant Proteins

Share to Serum Albumin

Source

Identifiers

PMID: 12069157
DOI: 10.1023/a:1015396825274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmaceutical strategies utilizing recombinant human serum albumin.PMID 12069157Read ↗

Design of yeast-secreted albumin derivatives for human therapy: biological and antiviral properties of a serum albumin-CD4 genetic conjugate.Semantic proximity Read ↗

Structural conservation and expanded functionality of hyper-stable human serum albumin variantsSemantic proximity Read ↗

Intracellular targeting with engineered proteinsSemantic proximity Read ↗

Development and characterization of fused human arginase I for cancer therapySemantic proximity Read ↗

Albumin-binding Aptamer Chimeras for Improved siRNA BioavailabilitySemantic proximity Read ↗

Gas vesicle-blood interactions enhance ultrasound imaging contrastSemantic proximity Read ↗

Extending Half-life by Indirect Targeting of the Neonatal Fc Receptor (FcRn) Using a Minimal Albumin Binding DomainSemantic proximity Read ↗

Pharmaceutically important pre- and posttranslational modifications on human serum albumin.Semantic proximity Read ↗

Optimized clinical performance of growth hormone with an expanded genetic code.Semantic proximity Read ↗

Silk Fibroin Particles as Carriers in the Development of All-Natural Hemoglobin-Based Oxygen Carriers (HBOCs)Semantic proximity Read ↗

Genetically Encoding a Lipidated Amino Acid for Extension of Protein Half‐Life in vivoSemantic proximity Read ↗

Formulation and biophysical characterization of SNARE’s like the behavior of human α-lactalbumin oleic acid (HALOA) complex as an anticancerous agent against chronic myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.