Article

Development and characterization of fused human arginase I for cancer therapy

2023-07-03

Abstract excerpt

Recombinant human arginase I (rhArg I) have emerged as a potential candidate for the treatment of varied pathophysiological conditions ranging from arginine-auxotrophic cancer, inflammatory conditions and microbial infection.. However, rhArg I have a low circulatory half-life, leading to poor pharmacokinetic and pharmacodynamic properties, which necessitating the rapid development of modifications to circumvent th...

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Identifiers and source

Literature Corpus work: 89593043-64fc-5be4-8831-b17d2b0c6f14
DOI: 10.21203/rs.3.rs-3118315/v1

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