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Article

Relationship between the platelet activating factor acetylhydrolase gene and intractability of ulcerative colitis.

Diseases of the colon and rectum - 1 Mar 2002

Nakamura Toshio, Sakaguchi Takanori, Unno Naoki, Sugatani Junko, Miwa Masao, Nakamura Satoshi

Abstract excerpt

PURPOSE: Platelet activating factor, which is a potent mediator of inflammatory injury in ulcerative colitis, is inactivated by platelet activating factor acetylhydrolase. Recently, a point mutation (G994 to T transversion) was observed in exon 9 of the platelet activating factor acetylhydrolase gene, and this mutation was found to be associated with a decrease in platelet activating factor acetylhydrolase...

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Identifiers

PMID: 12068200
DOI: 10.1007/s10350-004-6188-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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