Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deregulated platelet-activating factor levels and acetylhydrolase activity in patients with idiopathic IgA nephropathy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2000

Denizot Y, Aupetit C, Bridoux F, Alphonse J C, Cogné M, Aldigier J C

Abstract excerpt

BACKGROUND: Platelet-activating factor (PAF) is a phospholipid mediator with potent inflammatory activities. PAF stimulates IgA synthesis by B cells while IgA aggregates enhance PAF production by neutrophils and mesangial cells. These results led us to investigate blood PAF levels and plasma acetylhydrolase (AHA, the PAF catabolic enzyme) activity in patients with idiopathic IgA nephropathy (IgAN). METHODS: PAF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 1-Alkyl-2-acetylglycerophosphocholine Esterase
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Glomerulonephritis, IGA

Share to Mutation

Share to Phospholipases A

Source

Identifiers

PMID: 10978389
DOI: 10.1093/ndt/15.9.1344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deregulated platelet-activating factor levels and acetylhydrolase activity in patients with idiopathic IgA nephropathy.PMID 10978389Read ↗

Role of platelet-activating factor acetylhydrolase gene mutation in Japanese childhood IgA nephropathy.Semantic proximity Read ↗

Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.Semantic proximity Read ↗

Platelet-activating factor acetylhydrolases in health and disease.Semantic proximity Read ↗

Relationship between the platelet activating factor acetylhydrolase gene and intractability of ulcerative colitis.Semantic proximity Read ↗

Cellular source(s) of platelet-activating-factor acetylhydrolase activity in plasma.Semantic proximity Read ↗

Identification of the G994T polymorphism in exon 9 of plasma platelet-activating factor acetylhydrolase gene as a risk factor for polycystic ovary syndrome.Semantic proximity Read ↗

Plasma platelet-activating factor acetylhydrolase deficiency in Japanese patients with asthma.Semantic proximity Read ↗

Plasma platelet-activating factor acetylhydrolase deficiency is associated with atherosclerotic occlusive disease in japan.Semantic proximity Read ↗

Association of a G994 -->T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with risk of abdominal aortic aneurysm in Japanese.Semantic proximity Read ↗

Platelet-activating factor acetylhydrolase gene mutation in Japanese children with Escherichia coli O157-associated hemolytic uremic syndrome.Semantic proximity Read ↗

Platelet-activating factor acetylhydrolase gene mutation in Japanese nephrotic children.Semantic proximity Read ↗

Expression of Plasma Platelet-activating Factor Acetylhydrolase Is Transcriptionally Regulated by Mediators of InflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.