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Article

beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer.

Cancer research - 15 Jun 2002

Clements Wilson M, Wang Jiang, Sarnaik Amod, Kim On Ja, MacDonald Jack, Fenoglio-Preiser Cecilia, Groden Joanna, Lowy Andrew M

Abstract excerpt

Studies of Wnt activation in gastric cancer have yielded conflicting results. The goals of this study were to determine the frequency of Wnt pathway activation and beta-catenin mutation in these tumors. Three hundred eleven gastric cancers were examined for beta-catenin expression by immunostaining and dissected using laser capture microscopy to obtain DNA from those tumors with nuclear beta-catenin. Exon 3 of...

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PMID: 12067995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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