Article
Prenatal HLA genotyping of uncultured amniotic fluid samples contaminated with maternal blood.
American journal of obstetrics and gynecology - 1 Jun 2002
Eichler Hermann, Lese Andrea, Meckies Jessica, Zieger Wolfgang, Klüter Harald, Bugert Peter
Abstract excerpt
OBJECTIVE: Allogenic transplantation of umbilical cord blood (UCB) from HLA-identical siblings is a therapeutic concept of increasing importance. Prenatal HLA typing results can provide important information as to whether the UCB should be collected. Therefore, we tested the suitability of two methods based on polymerase chain reaction (PCR) for low-resolution HLA genotyping of uncultured amniocytes contaminated...
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