Article
Detection of maternal DNA in umbilical cord blood by polymerase chain reaction amplification of minisatellite sequences.
Bone marrow transplantation - 1 Jun 1998
Briz M, Regidor C, Monteagudo D, Somolinos N, Garaulet C, Forés R, Posada M, Fernández M N
Abstract excerpt
One of the concerns about the use of cord blood as a source of hematopoietic stem cells for allogeneic transplantation is the possibility of contamination by maternal cells which could cause life-threatening GVHD. We have assessed cord blood contamination using PCR analysis of several minisatellite regions to detect maternal DNA. Eighty mother-cord pairs were obtained for this study. In one case there were no...
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