Article
Detection of maternal deoxyribonucleic acid in umbilical cord plasma by using fluorescent polymerase chain reaction amplification of short tandem repeat sequences.
American journal of obstetrics and gynecology - 1 Jan 2002
Bauer Margit, Orescovic Irmgard, Schoell Wolfgang M, Bianchi Diana W, Pertl Barbara
Abstract excerpt
OBJECTIVE: Umbilical cord blood is a source of hematopoietic stem cells for transplantation. Although the first clinical applications have been encouraging, concern has been raised about contamination of umbilical blood by maternal cells, which might constitute a theoretical risk of graft-versus-host disease. The aim of this study was to assess the frequency of maternal deoxyribonucleic acid (DNA) contamination...
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