Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of HLA-DRB1-A and -B* alleles in prenatal diagnosis for determination of maternal contamination in fetal DNA.

Molecular human reproduction - 1 Jun 2002

Pietrapertosa A, Campanale D, Palma A, Renni R, D'Addario V, Tannoia N, Vitucci A

Abstract excerpt

During chorionic villi sampling for prenatal diagnosis with molecular biology techniques, contamination by maternal decidua frequently occurs and can lead to misinterpretation of the test results. To avoid such problems, we present a new method for appraising maternal contamination of fetal DNA, based on genomic typing of the highly variable human leukocyte antigen (HLA) locus-DRB1*, locus A* and locus B* regions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to DNA
Share to Fetus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Pregnancy

Share to Prenatal Diagnosis

Source

Identifiers

PMID: 12029078
DOI: 10.1093/molehr/8.6.586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of HLA-DRB1*-A* and -B* alleles in prenatal diagnosis for determination of maternal contamination in fetal DNA.PMID 12029078Read ↗

First trimester pregnancy loss: Clinical implications of genetic testingSemantic proximity Read ↗

A simple VNTR-PCR method for detecting maternal cell contamination in prenatal diagnosis.Semantic proximity Read ↗

Transabdominal placental biopsy in the second and third trimesters of pregnancy: what is the risk of maternal contamination in DNA diagnosis?Semantic proximity Read ↗

Prenatal HLA genotyping of uncultured amniotic fluid samples contaminated with maternal blood.Semantic proximity Read ↗

Detection of maternal DNA in umbilical cord blood by polymerase chain reaction amplification of minisatellite sequences.Semantic proximity Read ↗

Maternal cell contamination of prenatal samples assessed by QF-PCR genotyping.Semantic proximity Read ↗

A one-step real-time PCR assay for rapid prenatal diagnosis of sickle cell disease and detection of maternal contamination.Semantic proximity Read ↗

Analysis of cosegregation of intragenic DNA sequence variations as markers of maternal cell contamination in prenatal diagnosis of β-thalassemia.Semantic proximity Read ↗

Is the poly A (T>C) mutation a causative factor for misdiagnosis in second trimester prenatal diagnosis of β-thalassemia by fetal blood analysis on high performance liquid chromatography?Semantic proximity Read ↗

Prenatal diagnosis of beta-thalassaemia by chorionic villous sampling.Semantic proximity Read ↗

Is prenatal HLA typing of uncultured amniocytes before the collection of related allogenic cord blood helpful?Semantic proximity Read ↗

The sensitivity of allele-specific polymerase chain reaction can obviate concern of maternal contamination when fetal samples are genotyped for immune cytopenic disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.