Article
Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: relation to gross tumor morphology.
Gastroenterology - 1 Nov 1995
Ohashi K, Nakajima Y, Kanehiro H, Tsutsumi M, Taki J, Aomatsu Y, Yoshimura A, Ko S, Kin T, Yagura K
Abstract excerpt
BACKGROUND & AIMS: We previously reported that intrahepatic cholangiocarcinomas (ICCs) can be divided into three categories according to their gross appearance with possible links to biological behavior. Ki-ras and p53 gene alterations are thought to be involved in early and late phases of carcinogenesis, respectively. This study was performed to investigate the relationship between the gross appearance and...
Topics
- Adult
- Aged
- Base Sequence
- Cholangiocarcinoma
- Female
- Genes, ras
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation