Article
[Genotyping of multiple genetic alterations of intrahepatic cholangiocarcinoma].
Zhonghua yi xue za zhi - 10 Mar 2001
Cong W, Wu M, Chen H
Abstract excerpt
OBJECTIVE: To provide genetic evidence for understanding the mechanism of oncogenesis of intrahepatic cholangiocarcinoma (ICC) by detecting the multiple genetic spectrums. METHODS: Twenty-two cases of paraffin-embedded ICC tissue sections were microdissected and genotyped by PCR-based DNA sequencing to detect the frequencies of loss of heterozygosity (LOH) of tumor suppressor genes APC, MCC, DCC, OGG1, p53, and...
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