A second UDP-glucose pyrophosphorylase is required for differentiation and development in Dictyostelium discoideum.

doi:10.1074/jbc.M204245200

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A second UDP-glucose pyrophosphorylase is required for differentiation and development in Dictyostelium discoideum.

The Journal of biological chemistry - 6 Sept 2002

Bishop John D, Moon Byoung C, Harrow Faith, Ratner David, Gomer Richard H, Dottin Robert P, Brazill Derrick T

Abstract excerpt

Uridine diphosphoglucose pyrophosphorylase (UDPGP) is a developmentally regulated enzyme in Dictyostelium discoideum, which is involved in trehalose, cellulose, and glycogen synthesis. Two independent UDPGP proteins are believed to be responsible for this activity. To determine the relative contributions of each protein, the genes encoding them were disrupted individually. Cells lacking the udpgp1 gene exhibit...

Topics

Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
Cell Differentiation
Cell Division
Cell Survival
Cellulose
Cloning, Molecular
Dictyostelium
Escherichia coli

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Deletion

Gene Library

Genetic Complementation Test

Glycogen

Lysine

Models, Genetic

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 12060658
DOI: 10.1074/jbc.M204245200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A second UDP-glucose pyrophosphorylase is required for differentiation and development in Dictyostelium discoideum.PMID 12060658Read ↗

Polyphosphate kinase 1, a conserved bacterial enzyme, in a eukaryote, Dictyostelium discoideum, with a role in cytokinesis.Semantic proximity Read ↗

Gdt2 regulates the transition of Dictyostelium cells from growth to differentiation.Semantic proximity Read ↗

A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium.Semantic proximity Read ↗

Reverse genetic analyses of gamete-enriched genes revealed a novel regulator of the cAMP signaling pathway in Dictyostelium discoideum.Semantic proximity Read ↗

gdt1, a new signal transduction component for negative regulation of the growth-differentiation transition in Dictyostelium discoideum.Semantic proximity Read ↗

DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells.Semantic proximity Read ↗

Characterization of the Roco protein family in Dictyostelium discoideum.Semantic proximity Read ↗

Genetics of phototaxis in a model eukaryote, Dictyostelium discoideum.Semantic proximity Read ↗

Dictyostelium giganteum plasmid Dgp1 is a member of the Ddp2 plasmid family.Semantic proximity Read ↗

Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum.Semantic proximity Read ↗

DGAP1, a homologue of rasGTPase activating proteins that controls growth, cytokinesis, and development in Dictyostelium discoideum.Semantic proximity Read ↗

GidA is an FAD-binding protein involved in development of Myxococcus xanthus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.