Article
Polyphosphate kinase 1, a conserved bacterial enzyme, in a eukaryote, Dictyostelium discoideum, with a role in cytokinesis.
Proceedings of the National Academy of Sciences of the United States of America - 16 Oct 2007
Zhang Haiyu, Gómez-García María R, Shi Xiaobing, Rao Narayana N, Kornberg Arthur
Abstract excerpt
Polyphosphate kinase 1 (PPK1), the principal enzyme responsible for reversible synthesis of polyphosphate (poly P) from the terminal phosphate of ATP, is highly conserved in bacteria and archaea. Dictyostelium discoideum, a social slime mold, is one of a few eukaryotes known to possess a PPK1 homolog (DdPPK1). Compared with PPK1 of Escherichia coli, DdPPK1 contains the conserved residues for ATP binding and...
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