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Article

Decreased 4-aminopyridine sensitive K+ currents in endothelial cells from hypertensive rats.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jul 2002

Sadanaga Tsuneaki, Ohya Yusuke, Ohtsubo Toshio, Goto Kenichi, Fujii Koji, Abe Isao

Abstract excerpt

Endothelial cell function is altered in hypertension. The present study was performed to evaluate the alterations in K+ channels in endothelial cells from hypertensive rats. Currents and membrane potentials were recorded in endothelial cells freshly dissociated from the aorta of stroke-prone spontaneously hypertensive rats (SHR-SP) and Wistar-Kyoto rats (WKY). Ca2+-dependent K+ channel blockers, charybdotoxin and...

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Identifiers

PMID: 12358146
DOI: 10.1291/hypres.25.589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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