Article
Polymorphisms of the NOS3 gene in Southern Chilean subjects with coronary artery disease and controls.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2010
Jaramillo Priscilla C, Lanas Cecilia, Lanas Fernando, Salazar Luis A
Abstract excerpt
BACKGROUND: Nitric oxide (NO) from the endothelium, produced by oxidation of l-arginine to l-citruline for the action at the endothelial nitric oxide synthase (eNOS) is considered an important atheroprotective factor. The 894G>T, -786T>C and 4a/4b polymorphic variants of the NOS3 gene have been implicated in the development of coronary artery disease (CAD). We investigated the association between occurrence of...
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