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Article

Association between the NOS3 (-786 T/C) and the ACE (I/D) DNA genotypes and early coronary artery disease.

Nitric oxide : biology and chemistry - 1 Aug 2001

Alvarez R, González P, Batalla A, Reguero J R, Iglesias-Cubero G, Hevia S, Cortina A, Merino E, González I, Alvarez V, Coto E

Abstract excerpt

DNA polymorphisms at the endothelium constitutive nitric oxide synthase gene (NOS3) have been linked to the risk of developing coronary artery disease (CAD). In vitro, a polymorphism in the 5' region of the NOS3 gene (-786 T/C) influences promoter activity. This polymorphism has been associated w...

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Source

Identifiers

PMID: 11485372
DOI: 10.1006/niox.2001.0351

Genes

NOS3
ACE
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11485372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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