Article
Microtubule-associated proteins and motors required for ectopic microtubule array formation in Saccharomyces cerevisiae.
Genetics - 24 Jun 2021
King Brianna R, Meehl Janet B, Vojnar Tamira, Winey Mark, Muller Eric G, Davis Trisha N
Abstract excerpt
The mitotic spindle is resilient to perturbation due to the concerted, and sometimes redundant, action of motors and microtubule-associated proteins. Here, we utilize an inducible ectopic microtubule nucleation site in the nucleus of Saccharomyces cerevisiae to study three necessary steps in the formation of a bipolar array: the recruitment of the γ-tubulin complex, nucleation and elongation of microtubules...
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