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Article

Substrate specificity of nickel/cobalt permeases: insights from mutants altered in transmembrane domains I and II.

Journal of bacteriology - 1 Jul 2002

Degen Olaf, Eitinger Thomas

Abstract excerpt

HoxN, a high-affinity, nickel-specific permease of Ralstonia eutropha H16, and NhlF, a nickel/cobalt permease of Rhodococcus rhodochrous J1, are structurally related members of the nickel/cobalt transporter (NiCoT) family. These transporters have an eight-helix structure and are characterized by highly conserved segments with polar or charged amino acid residues in transmembrane domains (TMDs) II, III, V, and VI....

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Identifiers

PMID: 12057951
DOI: 10.1128/JB.184.13.3569-3577.2002
PMCID: PMC135128

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Source receipt: pubmed, retrieved 7 Sept 2026.

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