Article
Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST).
Journal of visualized experiments : JoVE - 23 Apr 2015
Sakic Boris, Cooper Marcella P A, Taylor Sarah E, Stojanovic Milica, Zagorac Bosa, Kapadia Minesh
Abstract excerpt
Due to rapid advances in genetic engineering, small rodents have become the preferred subjects in many disciplines of biomedical research. In studies of chronic CNS disorders, there is an increasing demand for murine models with high validity at the behavioral level. However, multiple pathogenic mechanisms and complex functional deficits often impose challenges to reliably measure and interpret behavior of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.