Article
[Genetic marker analysis in head and neck cancer]
Magyar onkologia - 1 Jan 2001
Csuka O, Olasz J, Juhász A, Hargitai A, Remenár E, Kásler M
Abstract excerpt
Prognostication of head and neck cancer (HNCC) involves molecular identification of residual tumor cells, prediction of recurrence, distant metastases or secondary tumors and prediction of the sensitvity to therapy. Biomarkers of HNCC are mutations of p53, p16 and amplification of Cyclin D and E2F4. One hundred and fifty-two HNCC cases have been evaluated for p53, hMLH1, Cyclin D and p16 gene alterations using...
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