Article
Self-analysis of repeat proteins reveals evolutionarily conserved patterns.
BMC bioinformatics - 7 May 2020
Merski Matthew, Młynarczyk Krzysztof, Ludwiczak Jan, Skrzeczkowski Jakub, Dunin-Horkawicz Stanisław, Górna Maria W
Abstract excerpt
BACKGROUND: Protein repeats can confound sequence analyses because the repetitiveness of their amino acid sequences lead to difficulties in identifying whether similar repeats are due to convergent or divergent evolution. We noted that the patterns derived from traditional "dot plot" protein sequence self-similarity analysis tended to be conserved in sets of related repeat proteins and this conservation could be...
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